Posiciones
| # | Equipo | PJ | PG | PE | PP | GF | GC | DG | Pts. |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Almeria | 11 | 7 | 1 | 3 | 21 | 10 | +11 | 22 |
| 2 | Eibar | 11 | 6 | 3 | 2 | 17 | 13 | +4 | 21 |
| 3 | Sporting Gijon | 11 | 6 | 3 | 2 | 14 | 10 | +4 | 21 |
| 4 | Ponferradina | 11 | 5 | 4 | 2 | 14 | 9 | +5 | 19 |
| 5 | FC Cartagena | 11 | 6 | 0 | 5 | 16 | 17 | -1 | 18 |
| 6 | Las Palmas | 11 | 4 | 5 | 2 | 15 | 13 | +2 | 17 |
| 7 | Tenerife | 11 | 5 | 2 | 4 | 13 | 11 | +2 | 17 |
| 8 | Real Valladolid | 11 | 4 | 4 | 3 | 13 | 11 | +2 | 16 |
| 9 | Huesca | 11 | 4 | 3 | 4 | 14 | 10 | +4 | 15 |
| 10 | Fuenlabrada | 11 | 3 | 6 | 2 | 9 | 7 | +2 | 15 |
| 11 | Lugo | 11 | 3 | 6 | 2 | 13 | 12 | +1 | 15 |
| 12 | Mirandes | 11 | 4 | 2 | 5 | 17 | 16 | +1 | 14 |
| 13 | Malaga | 11 | 3 | 5 | 3 | 9 | 12 | -3 | 14 |
| 14 | Burgos | 11 | 3 | 4 | 4 | 10 | 9 | +1 | 13 |
| 15 | Real Oviedo | 11 | 2 | 7 | 2 | 11 | 11 | +0 | 13 |
| 16 | Ibiza | 11 | 2 | 6 | 3 | 12 | 17 | -5 | 12 |
| 17 | Real Sociedad B | 11 | 2 | 5 | 4 | 11 | 13 | -2 | 11 |
| 18 | Real Zaragoza | 11 | 1 | 8 | 2 | 7 | 9 | -2 | 11 |
| 19 | Girona | 11 | 3 | 2 | 6 | 9 | 13 | -4 | 11 |
| 20 | Leganes | 11 | 2 | 4 | 5 | 11 | 15 | -4 | 10 |
| 21 | Amorebieta | 11 | 1 | 5 | 5 | 10 | 16 | -6 | 8 |
| 22 | Alcorcon | 11 | 2 | 1 | 8 | 9 | 21 | -12 | 7 |
Partidos
| 21/10/2021 | ||
| Real Oviedo | 1 - 3 | Burgos |
| Mirandes | 1 - 2 | Girona |
| Real Zaragoza | 1 - 1 | Ponferradina |
| Almeria | 3 - 1 | Real Sociedad B |
| 20/10/2021 | ||
| Lugo | 2 - 0 | Las Palmas |
| Alcorcon | 3 - 3 | Leganes |
| Fuenlabrada | 0 - 0 | Amorebieta |
| Real Valladolid | 1 - 1 | Ibiza |
| 19/10/2021 | ||
| Tenerife | 0 - 1 | Eibar |
| Huesca | 0 - 0 | Malaga |
| FC Cartagena | 1 - 0 | Sporting Gijon |
| 17/10/2021 | ||
| Ponferradina | 0 - 0 | Fuenlabrada |
| Real Sociedad B | 1 - 1 | Real Oviedo |
| Burgos | 1 - 1 | Lugo |
| Leganes | 0 - 2 | Real Valladolid |
| Ibiza | 0 - 2 | Mirandes |
| 22/10/2021 | ||
| Eibar | 16:00 | FC Cartagena |
| 23/10/2021 | ||
| Ibiza | 11:00 | Fuenlabrada |
| Sporting Gijon | 13:15 | Real Valladolid |
| Malaga | 15:30 | Lugo |
| Leganes | 16:00 | Tenerife |
| 24/10/2021 | ||
| Mirandes | 09:00 | Almeria |
| Amorebieta | 09:00 | Real Sociedad B |
| Ponferradina | 13:15 | Real Oviedo |
| Burgos | 13:15 | Huesca |
| Las Palmas | 16:00 | Alcorcon |
| 25/10/2021 | ||
| Girona | 16:00 | Real Zaragoza |
| 29/10/2021 | ||
| Real Sociedad B | 16:00 | Las Palmas |
| Almeria | 16:00 | Leganes |
| 30/10/2021 | ||
| Huesca | 11:00 | Amorebieta |
| Lugo | 13:15 | Sporting Gijon |
| FC Cartagena | 16:00 | Ponferradina |
| 31/10/2021 | ||
| Fuenlabrada | 11:00 | Girona |
| Real Oviedo | 13:00 | Malaga |
| Real Valladolid | 15:15 | Eibar |
| Real Zaragoza | 17:30 | Mirandes |
